What is the Association between the Microbiome and Cognition? An Umbrella Review

This project plans to conduct an umbrella review — that means it will systematically collect and analyze the results of multiple existing systematic reviews — to understand the relationship between the microbiome (the community of microbes in the human body) and cognition (how the brain thinks and functions). The researchers will look across a wide range of conditions where cognitive problems occur (like Alzheimer’s, Parkinson’s, long-COVID “brain fog,” and others) and see how changes in the microbiome are linked with cognitive outcomes. They will also examine what microbiome-targeted or related interventions have been studied and how they might influence cognition, aiming to identify consistent patterns across different populations and conditions. 

The protocol for this project is published and available online: 

https://bmjopen.bmj.com/content/bmjopen/14/6/e077873.full.pdf